PROCESS FOR PRODUCING POLYMORPHIC FORM I OF D4T (2',3'-DIDEHYDRO-3'-DEOXY-TIMIDINE)

The present invention concerns a novel process using controlled cooling for obtaining d4T polymorphic Form I from a mixture containing one or more of polymorphic Forms I, II and III. Compound d4T has been approved for use in the treatment of AIDS.

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Bibliographische Detailangaben
Hauptverfasser:	GAROFALO,PETER MICHAEL, PERRONE,ROBERT KEVIN, KAPLAN,MURRAY ARTHUR, BOGARDUS,JOSEPH BALLARD, MARR,TIMOTHY RICHARD, GANDHI,RAJESH BABULAL
Format:	Patent
Sprache:	eng
Schlagworte:	APPARATUS THEREFOR CHEMISTRY DERIVATIVES THEREOF GENERAL METHODS OF ORGANIC CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY NUCLEIC ACIDS NUCLEOSIDES NUCLEOTIDES ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SUGARS
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Beschreibung
Zusammenfassung:	The present invention concerns a novel process using controlled cooling for obtaining d4T polymorphic Form I from a mixture containing one or more of polymorphic Forms I, II and III. Compound d4T has been approved for use in the treatment of AIDS.