Low dose, stable drug-release transdermal composition and patch, as well as method for preparation thereof

The invention relates to a topical, preferably transdermal preparation and patch, which can deliver its active ingredient content into the skin with near zero-order kinetics, as well as a method for their production. The active ingredient is preferably an NSAID or a capsaicinoid. In particular, the invention relates to a transdermal patch comprising a low dose of capsaicin, which, when placed on the skin, ensures the release of the active ingredient over a long period of time, preferably for 4 to 24 hours, more preferably for 6-12 hours, with near zero-order kinetics. The invention further relates to the production of these preparations. The invention further relates to the use of these preparations to relieve pain, preferably acute pain, and/or chronic inflammatory and neuropathic pain, and as a warm-up patch during sports activities.