Pimavanserin salts for the manufacture of pharmaceutical formulations

Pimavanserin salts for the manufacture of pharmaceutical formulations

The object of the present invention relates to the formula (1) 1-(4-fluorobenzyl)-1-(1- methylpiperidin-4-yl)-3-[4-(2-methylpropoxy)benzyl]carbamide (pimavanserin) besylate, cyclamate, tosylate, benzoate and mandelate salts, as well as to their amorphous and crystalline forms, their hydrates and sol...

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Bibliographische Detailangaben
Hauptverfasser: Molnarne dr. Samu Erika, Tothne Dr. Lauritz Maria, dr. Volk Balazs, Keszthelyi Adrienn, Szlavik Laszlo, Kataine Fadgyas Katalin, Racz Norbert, dr. Nagy Tamas, Varga Zoltan, dr. Detrich Adam Dezsoe
Format: Patent
Sprache:eng ; hun
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Beschreibung
Zusammenfassung:The object of the present invention relates to the formula (1) 1-(4-fluorobenzyl)-1-(1- methylpiperidin-4-yl)-3-[4-(2-methylpropoxy)benzyl]carbamide (pimavanserin) besylate, cyclamate, tosylate, benzoate and mandelate salts, as well as to their amorphous and crystalline forms, their hydrates and solvates, to the production of these salts, and to pharmaceutical preparations containing these, as well as to the therapeutic use of these salts.