Complexes of lumacaftor and its salts and derivatives, process for the preparation thereof and pharmaceutical compositions containing them
The present invention relates to pharmaceutically acceptable complex formulation comprising complexes of Lumacaftor, or a salt, or derivatives thereof and complexation agents and pharmaceutically acceptable excipients, process for the preparation thereof and pharmaceutical compositions containing th...
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| Hauptverfasser: | , , , , , , , , |
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| Format: | Patent |
| Sprache: | eng ; hun |
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| Zusammenfassung: | The present invention relates to pharmaceutically acceptable complex formulation comprising complexes of Lumacaftor, or a salt, or derivatives thereof and complexation agents and pharmaceutically acceptable excipients, process for the preparation thereof and pharmaceutical compositions containing them. The complex formulations of the present invention have improved dissolution and permeability in fasted and fed state simulation that is expected to deliver full absorption and the elimination of the food effect. |
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