Method for producing morphologically pure mirabegron and mirabegron monohydrochloride

The object of the present invention relates to a method for the production of formula 1 (R)-2- (2-aminothiazole-4-yl)-4'-[2-[(2-hydroxy-2-phenyl)ethylamino]ethyl]acetanilide (mirabegron) and formula 1c mirabegron monohydrochloride, as well as the intermediates used during the method.

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Bibliographische Detailangaben
Hauptverfasser: dr. Volk Balazs, Tothne Dr. Lauritz Maria, Virag Attila, Kataine Fadgyas Katalin, dr. Nagy Tamas, Varga Zoltan, dr. Dancso Andras, dr. Mravik Andras, dr. Nemeth Gabor
Format: Patent
Sprache:eng ; hun
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Beschreibung
Zusammenfassung:The object of the present invention relates to a method for the production of formula 1 (R)-2- (2-aminothiazole-4-yl)-4'-[2-[(2-hydroxy-2-phenyl)ethylamino]ethyl]acetanilide (mirabegron) and formula 1c mirabegron monohydrochloride, as well as the intermediates used during the method.