KYNURENC ACID DERIVATIVES, PROCESS FOR THEIR PREPARATION, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USE FOR THE TREATMENT OF HEADACHE

KYNURENC ACID DERIVATIVES, PROCESS FOR THEIR PREPARATION, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USE FOR THE TREATMENT OF HEADACHE

The present invention is directed to novel kynurenic acid (KYNA) derivatives of the general formula (I) - and pharmaceutically acceptable salts, amides, all possible stereoisomers, including diastereoisomers and/or enantiomers, racemates and mixtures thereof, as well as a process for the preparation...

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Hauptverfasser: KASZAKI JOZSEF DR, VECSEI LASZLO DR, PARDUTZ ARPAD DR, TAJTI JANOS DR, KNYIHAR ERZSEBET DR, TOLDI JOZSEF DR, SZATMARI ISTVAN DR, FUELOEP FERENC DR, VARGA HEDVIG, BOROS MIHALY DR, VAMOS ENIKOE
Format: Patent
Sprache:eng ; hun
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Zusammenfassung:The present invention is directed to novel kynurenic acid (KYNA) derivatives of the general formula (I) - and pharmaceutically acceptable salts, amides, all possible stereoisomers, including diastereoisomers and/or enantiomers, racemates and mixtures thereof, as well as a process for the preparation thereof, pharmaceutical compositions containing same, and use thereof for the manufacture of pharmaceutical compositions useful in the treatment of headaches, particularly non- neurodegenerative migraine.