PROCESS FOR PRODUCING ROSUVASTATIN SALT

PROCESS FOR PRODUCING ROSUVASTATIN SALT

The subject of the present invention is an improved process for the preparation of (+)-7-[4-(4-fluorophenyl)-6-isopropyl-2-(methanesulfonyl-methyl-amino)-pyrimidin-5-yl]-(3i-,55)-dihydroxy-hept-6-enoic acid zinc salt (2:1), which allows the reproducible manufacture of said compound on industrial sca...

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Hauptverfasser: BARTHA FERENC, KIRALY IMRE, NAGY KALMAN DR, MEZEI TIBOR DR, RUZSICS GYOERGY, BARKOCZY JOZSEF, VOLK BALAZS, KARASZ ADRIENN, TOEMPE PETER DR, SIMIG GYULA DR, VAGO PAL DR
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Sprache:eng ; hun
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creator BARTHA FERENC
KIRALY IMRE
NAGY KALMAN DR
MEZEI TIBOR DR
RUZSICS GYOERGY
BARKOCZY JOZSEF
VOLK BALAZS
KARASZ ADRIENN
TOEMPE PETER DR
SIMIG GYULA DR
VAGO PAL DR
description The subject of the present invention is an improved process for the preparation of (+)-7-[4-(4-fluorophenyl)-6-isopropyl-2-(methanesulfonyl-methyl-amino)-pyrimidin-5-yl]-(3i-,55)-dihydroxy-hept-6-enoic acid zinc salt (2:1), which allows the reproducible manufacture of said compound on industrial scale in high purity. The compound of the Formula (I) can be used for the treatment of diseases related to lipid metabolism.
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title PROCESS FOR PRODUCING ROSUVASTATIN SALT
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