PROCESS FOR PRODUCING ROSUVASTATIN SALT

The subject of the present invention is an improved process for the preparation of (+)-7-[4-(4-fluorophenyl)-6-isopropyl-2-(methanesulfonyl-methyl-amino)-pyrimidin-5-yl]-(3i-,55)-dihydroxy-hept-6-enoic acid zinc salt (2:1), which allows the reproducible manufacture of said compound on industrial sca...

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Bibliographische Detailangaben
Hauptverfasser: BARTHA FERENC, KIRALY IMRE, NAGY KALMAN DR, MEZEI TIBOR DR, RUZSICS GYOERGY, BARKOCZY JOZSEF, VOLK BALAZS, KARASZ ADRIENN, TOEMPE PETER DR, SIMIG GYULA DR, VAGO PAL DR
Format: Patent
Sprache:eng ; hun
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Beschreibung
Zusammenfassung:The subject of the present invention is an improved process for the preparation of (+)-7-[4-(4-fluorophenyl)-6-isopropyl-2-(methanesulfonyl-methyl-amino)-pyrimidin-5-yl]-(3i-,55)-dihydroxy-hept-6-enoic acid zinc salt (2:1), which allows the reproducible manufacture of said compound on industrial scale in high purity. The compound of the Formula (I) can be used for the treatment of diseases related to lipid metabolism.