PD-L1 VARIANT IMMUNOMODULATORY PROTEINS AND USES THEREOF

PD-L1 VARIANT IMMUNOMODULATORY PROTEINS AND USES THEREOF

Provided herein are immunomodulatory proteins comprising variant PD-LI and nucleic acids encoding such proteins. The immunomodulatory proteins provide therapeutic utility for a variety of immunological and oncological conditions. Compositions and methods for making and using such proteins are provid...

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Bibliographische Detailangaben
Hauptverfasser: MAURER, Mark F, KORNACKER, Michael, KUIJPER, Joseph L, ARDOUREL, Dan, DEMONTE, Daniel William, SWANSON, Ryan
Format: Patent
Sprache:eng ; hun
Schlagworte:
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:Provided herein are immunomodulatory proteins comprising variant PD-LI and nucleic acids encoding such proteins. The immunomodulatory proteins provide therapeutic utility for a variety of immunological and oncological conditions. Compositions and methods for making and using such proteins are provided.