PROLONGED RELEASE DOSAGE FORM OF TAPENTADOL L-(+)- TARTARIC ACID SALT

PROLONGED RELEASE DOSAGE FORM OF TAPENTADOL L-(+)- TARTARIC ACID SALT

Dosage Form Providing Prolonged Release of a Salt of Tapentadol with L-(+)-Tartaric Acid Abstract: The invention relates to a tablet providing prolonged release of Tapentadol, wherein Tapentadol is present in the form of a salt with tartaric acid, in particular in the form of a salt with L-(+)-tarta...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: BERTRAM, Ulrike, REINHOLD, Ulrich, GROSSE, Christian, HARTMANN, Carmen
Format: Patent
Sprache:eng ; hun
Schlagworte:
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:Dosage Form Providing Prolonged Release of a Salt of Tapentadol with L-(+)-Tartaric Acid Abstract: The invention relates to a tablet providing prolonged release of Tapentadol, wherein Tapentadol is present in the form of a salt with tartaric acid, in particular in the form of a salt with L-(+)-tartaric acid. The tablet has satisfactory mechanical properties, for example, with regard to breaking strength and friability, and it can be produced under considerably facilitated tableting conditions, in particular at reduced compression force.