HYDROXYLATED POLYAMINE DERIVATIVES AS TRANSFECTION REAGENTS

The invention provides hydroxylated polyamine derivatives, their use for the transfection of RNA polyanions into cells, and a method of transfecting cells with a polyanion, comprising mixing said polyanion with said hydroxylated polyamine derivative in a buffer and treating said cells with the mixtu...

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Bibliographische Detailangaben
Hauptverfasser: REINSCH, Christian, Panzner, Steffen, WENDISCH, Volkmar, DREHER, Christina
Format: Patent
Sprache:eng ; hun
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Beschreibung
Zusammenfassung:The invention provides hydroxylated polyamine derivatives, their use for the transfection of RNA polyanions into cells, and a method of transfecting cells with a polyanion, comprising mixing said polyanion with said hydroxylated polyamine derivative in a buffer and treating said cells with the mixture obtained in the previous step.