IMMUNOREGULATORY AGENTS

Compounds that modulate the oxidoreductase enzyme indoleamine 2,3- dioxygenase, and compositions containing the compounds, are described herein. The use of such compounds and compositions for the treatment and/or prevention of a diverse array of diseases, disorders and conditions, including cancer-...

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Hauptverfasser: REILLY, Maureen Kay, JAEN, Juan Carlos, HUANG, Audris, SHAN, Weifang, POWERS, Jay Patrick, WALKER, James Ross, BALOG, James Aaron, WILLIAMS, David K, MARKWALDER, Jay A, BECK, Hilary Plake, CHERNEY, Emily Charlotte, OSIPOV, Maksim, SHUNATONA, Hunter Paul, ZIBINSKY, Mikhail
Format: Patent
Sprache:eng ; hun
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Zusammenfassung:Compounds that modulate the oxidoreductase enzyme indoleamine 2,3- dioxygenase, and compositions containing the compounds, are described herein. The use of such compounds and compositions for the treatment and/or prevention of a diverse array of diseases, disorders and conditions, including cancer- and immune-related disorders, that are mediated by indoleamine 2,3-dioxygenase is also provided.