TRIAZOLES FOR REGULATING INTRACELLULAR CALCIUM HOMEOSTASIS

The present invention relates to 1,2,3-triazoles of formula: useful for improving or restoring the intracellular calcium homeostasis and RyR-calstabin binding function in human and animal cells. The present invention also relates to methods for synthesizing said compounds, to pharmaceutical composit...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: FERRON CELMA, Pablo, IRASTORZA EPELDE, Aitziber, VALLEJO ILLARRAMENDI, Ainara, MIRANDA MURUA, Jose Ignacio, ALDANONDO ARISTIZABAL, Garazi, LOPEZ DE MUNAIN ARREGI, Adolfo Jose, AIZPURUA IPARRAGUIRRE, Jesus Maria, TORAL OJEDA, Ivan
Format: Patent
Sprache:eng ; hun
Schlagworte:
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:The present invention relates to 1,2,3-triazoles of formula: useful for improving or restoring the intracellular calcium homeostasis and RyR-calstabin binding function in human and animal cells. The present invention also relates to methods for synthesizing said compounds, to pharmaceutical compositions containing them, and to the use thereof for preventing or treating skeletal muscle, heart and nervous system disorders.