PHARMACEUTICAL COMPOSITION FOR MODIFIED RELEASE

A controlled release pharmaceutical composition containing (1) (R)-2-(2-aminothiazol-4-yl)-4'-[2-[(2-hydroxy-2-phenylethyl)ammino]ethyl]acetic acid anilide or a pharmaceutically acceptable salt thereof, (2) one or more additives for having water seep into the inside of the preparation, said add...

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Bibliographische Detailangaben
Hauptverfasser: MURAYAMA, Emiko, TAKAISHI, Yuuki, NISHIZATO, Takashi, SAKO, Kazuhiro, MURAYAMA, Daisuke, TAKAHASHI, Yutaka, NAKAMURA, Soichiro
Format: Patent
Sprache:eng ; hun
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Zusammenfassung:A controlled release pharmaceutical composition containing (1) (R)-2-(2-aminothiazol-4-yl)-4'-[2-[(2-hydroxy-2-phenylethyl)ammino]ethyl]acetic acid anilide or a pharmaceutically acceptable salt thereof, (2) one or more additives for having water seep into the inside of the preparation, said additives having such a solubility that the amount of water required for dissolving 1g of the additives is not more than 10 mL, and (3) a polymer material for forming a hydrogel, said polymer material having an average molecular weight of about 100,000 or more and a viscosity of not less than 12 mPa·s as measured in the form of a 5% aqueous solution at 25°C.