TABLET FORMULATIONS OF NERATINIB MALEATE

The invention provides a high strength neratinib tablet and a method of its manufacturing comprising spraying intragranular components of a granulation comprising neratinib maleate, fillers, disintegrants and glidants, with a surface modifying agent and combining them with extragranular components c...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: NAGI, Arwinder Singh, GHOSH, Krishnendu, MAHMUD, Mainuddin, ASHRAF, Muhammad, GOOLCHARRAN, Chimanlall
Format: Patent
Sprache:eng ; hun
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Beschreibung
Zusammenfassung:The invention provides a high strength neratinib tablet and a method of its manufacturing comprising spraying intragranular components of a granulation comprising neratinib maleate, fillers, disintegrants and glidants, with a surface modifying agent and combining them with extragranular components comprising fillers, disintegrants and lubricants.