BIOCATALYSTS FOR THE PREPARATION OF HYDROXY SUBSTITUTED CARBAMATES

The present disclosure relates to engineered ketoreductase polypeptides for the preparation of hydroxyl substituted carbamate compounds, and polynucleotides, vectors, host cells, and methods of making and using the ketoreductase polypeptides.

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Bibliographische Detailangaben
Hauptverfasser: KOSJEK, Birgit, JANEY, Jacob, CHEN, Haibin, CABIROL, Fabien, COLLIER, Steven, SMITH, Derek, GOHEL, Anupam
Format: Patent
Sprache:eng ; hun
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Beschreibung
Zusammenfassung:The present disclosure relates to engineered ketoreductase polypeptides for the preparation of hydroxyl substituted carbamate compounds, and polynucleotides, vectors, host cells, and methods of making and using the ketoreductase polypeptides.