HUMANIZED IL-25 ANTIBODIES

HUMANIZED IL-25 ANTIBODIES

The present invention relates to target binding members (e.g., antibodies) that bind a specified epitope of human IL-25. The invention also relates to target binding members (e.g., antibodies) that comprise one or more humanized antibody VL domain sequences and bind IL-25. The invention further rela...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: WHEELER, John, TAUDTE, Susann, ALMAGRO, Juan, STROHL, William, TORNETTA, Mark, BRANIGAN, Patrick, KANE, Colleen
Format: Patent
Sprache:eng ; hun
Schlagworte:
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
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Beschreibung
Zusammenfassung:The present invention relates to target binding members (e.g., antibodies) that bind a specified epitope of human IL-25. The invention also relates to target binding members (e.g., antibodies) that comprise one or more humanized antibody VL domain sequences and bind IL-25. The invention further relates to compositions comprising target binding members (e.g., antibodies) that bind IL-25, methods of producing such target binding members, and uses of such target binding members for the treatment or prevention of diseases and conditions (e.g., asthma, inflammatory bowel disease).