USE OF POLYOLS TO OBTAIN STABLE POLYMORPHOUS FORMS OF RIFAXIMIN

USE OF POLYOLS TO OBTAIN STABLE POLYMORPHOUS FORMS OF RIFAXIMIN

Polyols stabilize polymorphous form of rifaximin, in particular the ² form. When polyols having at least two hydroxy groups are added to rifaximin powder, polymorph ² is stable and remains stable in time independently from the environment humidity. In this invention a method to prepare formulations...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: BOTTONI, Giuseppe, MAFFEI, Paola, VISCOMI, Giuseppe, Claudio, BACHETTI, Milena
Format: Patent
Sprache:eng ; hun
Schlagworte:
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Polyols stabilize polymorphous form of rifaximin, in particular the ² form. When polyols having at least two hydroxy groups are added to rifaximin powder, polymorph ² is stable and remains stable in time independently from the environment humidity. In this invention a method to prepare formulations constituted by pure and stable polymorphous forms able to give a pharmaceutical product is described.