ALIPHATIC AMINE POLYMER SALTS FOR TABLETING

ALIPHATIC AMINE POLYMER SALTS FOR TABLETING

The tablets, compositions and methods of the present invention, comprising a carbonate salt of an aliphatic amine polymer and s monovalent anion can prevent or ameliorate acidosis, in particular acidosis in patients with renal disease. The tablets and compositions of the present invention maintain a...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: GOLDBERG, Jeffery, Marc, HARIANAWALA, Abizer, BHAGAT, Hitesh, BRENNER, Louis
Format: Patent
Sprache:eng ; hun
Schlagworte:
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:The tablets, compositions and methods of the present invention, comprising a carbonate salt of an aliphatic amine polymer and s monovalent anion can prevent or ameliorate acidosis, in particular acidosis in patients with renal disease. The tablets and compositions of the present invention maintain a disintegration time of no greater than 30 minutes at 37°C and at pH of at least 1 for a period of at least ten weeks at 60°C. Furthermore, the tablets are stable for extended periods of time without the need for specialized storage conditions.