OPSIN-BINDING LIGANDS, COMPOSITIONS AND METHODS OF USE

OPSIN-BINDING LIGANDS, COMPOSITIONS AND METHODS OF USE

Compounds and compositions of said compounds along with methods of use of compounds are disclosed for treating ophthalmic conditions related to mislocalization of opsin proteins, the misfolding of mutant opsin proteins and the production of toxic visual cycle products that accumulate in the eye. Com...

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Bibliographische Detailangaben
Hauptverfasser: GARVEY, David, S, LAROSA, Gregory, J, GREENWOOD, Jeremy, Robert, BREWER, Mark, L, COTE, Jamie, B, QUACH, Tan, BERMAN, Judd
Format: Patent
Sprache:eng ; hun
Schlagworte:
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:Compounds and compositions of said compounds along with methods of use of compounds are disclosed for treating ophthalmic conditions related to mislocalization of opsin proteins, the misfolding of mutant opsin proteins and the production of toxic visual cycle products that accumulate in the eye. Compounds and compositions useful in these methods, either alone or in combination with other therapeutic agents, are also described.