VIABLE NON-TOXIC GRAM NEGATIVE BACTERIA

The present invention provides non-toxic Gram-negative bacteria. In particular, the present invention provides viable Gram-negative bacteria (e.g., E. coli) substantially lacking lipopolysaccharide (LPS, endotoxin) within the outer membrane. The present invention further provides methods of generati...

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Bibliographische Detailangaben
Hauptverfasser: WOODARD, Ronald Wesley, MEREDITH, Timothy Charles, AGGARWAL, Parag
Format: Patent
Sprache:eng ; hun
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Zusammenfassung:The present invention provides non-toxic Gram-negative bacteria. In particular, the present invention provides viable Gram-negative bacteria (e.g., E. coli) substantially lacking lipopolysaccharide (LPS, endotoxin) within the outer membrane. The present invention further provides methods of generating viable non-toxic Gram-negative bacteria and uses thereof. The present invention also provides compositions and methods for inducing immune responses and for researching and developing therapeutic agents.