Unitary pharmaceutical dosage form comprising Tenofovir DF, Emtricitabine, Efavirenz and a surfactant

Unitary pharmaceutical dosage form comprising Tenofovir DF, Emtricitabine, Efavirenz and a surfactant

In accordance with this invention a novel pharmaceutical product containing efavirenz, emtricitabine and tenofovir DF are provided as a multicomponent unitary oral dosage form, component 1 comprising tenofovir DF (and, optionally, emtricitabine) and component 2 comprising efavirenz, wherein componen...

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Hauptverfasser: YANG, Taiyin, Jerzewski, Robert, L, MENNING, Mark, M, Hussain, Munir, A, DAHL, Terrence, C, OLIYAI, Reza, Lipper, Robert, A
Format: Patent
Sprache:eng ; hun
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HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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creator YANG, Taiyin
Jerzewski, Robert, L
MENNING, Mark, M
Hussain, Munir, A
DAHL, Terrence, C
OLIYAI, Reza
Lipper, Robert, A
description In accordance with this invention a novel pharmaceutical product containing efavirenz, emtricitabine and tenofovir DF are provided as a multicomponent unitary oral dosage form, component 1 comprising tenofovir DF (and, optionally, emtricitabine) and component 2 comprising efavirenz, wherein components 1 and 2 are in a stabilizing configuration. In preferred embodiments component 1 is made by dry granulation.
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title Unitary pharmaceutical dosage form comprising Tenofovir DF, Emtricitabine, Efavirenz and a surfactant
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