Unitary pharmaceutical dosage form comprising Tenofovir DF, Emtricitabine, Efavirenz and a surfactant

Unitary pharmaceutical dosage form comprising Tenofovir DF, Emtricitabine, Efavirenz and a surfactant

In accordance with this invention a novel pharmaceutical product containing efavirenz, emtricitabine and tenofovir DF are provided as a multicomponent unitary oral dosage form, component 1 comprising tenofovir DF (and, optionally, emtricitabine) and component 2 comprising efavirenz, wherein componen...

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Bibliographische Detailangaben
Hauptverfasser: YANG, Taiyin, Jerzewski, Robert, L, MENNING, Mark, M, Hussain, Munir, A, DAHL, Terrence, C, OLIYAI, Reza, Lipper, Robert, A
Format: Patent
Sprache:eng ; hun
Schlagworte:
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:In accordance with this invention a novel pharmaceutical product containing efavirenz, emtricitabine and tenofovir DF are provided as a multicomponent unitary oral dosage form, component 1 comprising tenofovir DF (and, optionally, emtricitabine) and component 2 comprising efavirenz, wherein components 1 and 2 are in a stabilizing configuration. In preferred embodiments component 1 is made by dry granulation.