METHOD FOR PRODUCING 5-(1-PIPERAZINYL)-BENZOFURAN-2-CARBOXAMIDE BY TRANSITION METAL-CATALYZED AMINATION

Process for the preparation of 5-(1-piperazinyl)benzofuran-2-carboxamide in which, as intermediate step, 5-bromosalicylaldehyde or one of its derivatives is reacted in a transition metal-catalysed amination with R -piperazine, in which R is as defined in claim 1.

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Bibliographische Detailangaben
Hauptverfasser: HELFERT, BERND, EMMERT, STEFFEN, BATHE, ANDREAS, BOETTCHER, HENNING
Format: Patent
Sprache:eng ; hun
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Zusammenfassung:Process for the preparation of 5-(1-piperazinyl)benzofuran-2-carboxamide in which, as intermediate step, 5-bromosalicylaldehyde or one of its derivatives is reacted in a transition metal-catalysed amination with R -piperazine, in which R is as defined in claim 1.