NOVEL PROCESS FOR THE PREPARATION OF 6-METHYL-2-(4-METHYL-PHENYL)-IMIDAZO[1,2-A]PYRIMIDYNE-3-(N,N-DIMETHYL-ACETAMIDE)
6-methyl-2-(4-methyl-phenyl)-imidazo(1,2- a)pyrimidine-3-(N,N-dimethyl-acetamide) (I) is prepared by reaction of an acetate ester (II) with dimethylamine in a polar aprotic solvent. Preparation of a compound of formula (I), or an acid addition salt of (I), comprises: (a) reaction of an ester compoun...
Gespeichert in:
| Hauptverfasser: | , , , , , , , , |
|---|---|
| Format: | Patent |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext bestellen |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | |
| container_start_page | |
| container_title | |
| container_volume | |
| creator | PONGO LASZLO DR NAGY KALMAN DR REITER JOSZEF DR TOMPE PUTER DR HOFFMANNU FEKETE VALURIA RYVO ENDRE DR KONCZ LASZLO SIMIG GYULA DR VERECZKEYNU DONATH GYORGYI DR |
| description | 6-methyl-2-(4-methyl-phenyl)-imidazo(1,2- a)pyrimidine-3-(N,N-dimethyl-acetamide) (I) is prepared by reaction of an acetate ester (II) with dimethylamine in a polar aprotic solvent. Preparation of a compound of formula (I), or an acid addition salt of (I), comprises: (a) reaction of an ester compound of formula (II) with dimethylamine in a polar aprotic solvent; and optionally (b) converting the product (I) into an acid addition salt. R = lower alkyl or phenyl-lower alky.l Independent claims are included for: (i) esters (II), with the exception of (II; R = ethyl), and (ii) crystalline esters of formula (II). |
| format | Patent |
| fullrecord | <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_HU227358B1</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>HU227358B1</sourcerecordid><originalsourceid>FETCH-epo_espacenet_HU227358B13</originalsourceid><addsrcrecordid>eNqFiz0LwjAYhLs4iPobzNhC36GpX2ts35JAm4Q0ClGkFImTaKH6_61QZ6e7e-5uGrylOmJJtFEZ1jUplCGW45BRM8OsUJKogmygQstdCRTC1c9rjtKVEYhK5OykzklMgV20M1_gJEIKoYwl5GI8sAwtGzqM5sHk1t57vxh1FiwLtBkH3z0b33ft1T_8q-EHSrfperdP0v-LD7q4N8k</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>NOVEL PROCESS FOR THE PREPARATION OF 6-METHYL-2-(4-METHYL-PHENYL)-IMIDAZO[1,2-A]PYRIMIDYNE-3-(N,N-DIMETHYL-ACETAMIDE)</title><source>esp@cenet</source><creator>PONGO LASZLO DR ; NAGY KALMAN DR ; REITER JOSZEF DR ; TOMPE PUTER DR ; HOFFMANNU FEKETE VALURIA ; RYVO ENDRE DR ; KONCZ LASZLO ; SIMIG GYULA DR ; VERECZKEYNU DONATH GYORGYI DR</creator><creatorcontrib>PONGO LASZLO DR ; NAGY KALMAN DR ; REITER JOSZEF DR ; TOMPE PUTER DR ; HOFFMANNU FEKETE VALURIA ; RYVO ENDRE DR ; KONCZ LASZLO ; SIMIG GYULA DR ; VERECZKEYNU DONATH GYORGYI DR</creatorcontrib><description>6-methyl-2-(4-methyl-phenyl)-imidazo(1,2- a)pyrimidine-3-(N,N-dimethyl-acetamide) (I) is prepared by reaction of an acetate ester (II) with dimethylamine in a polar aprotic solvent. Preparation of a compound of formula (I), or an acid addition salt of (I), comprises: (a) reaction of an ester compound of formula (II) with dimethylamine in a polar aprotic solvent; and optionally (b) converting the product (I) into an acid addition salt. R = lower alkyl or phenyl-lower alky.l Independent claims are included for: (i) esters (II), with the exception of (II; R = ethyl), and (ii) crystalline esters of formula (II).</description><language>eng</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; METALLURGY ; ORGANIC CHEMISTRY</subject><creationdate>2011</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20110428&DB=EPODOC&CC=HU&NR=227358B1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,778,883,25551,76302</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20110428&DB=EPODOC&CC=HU&NR=227358B1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>PONGO LASZLO DR</creatorcontrib><creatorcontrib>NAGY KALMAN DR</creatorcontrib><creatorcontrib>REITER JOSZEF DR</creatorcontrib><creatorcontrib>TOMPE PUTER DR</creatorcontrib><creatorcontrib>HOFFMANNU FEKETE VALURIA</creatorcontrib><creatorcontrib>RYVO ENDRE DR</creatorcontrib><creatorcontrib>KONCZ LASZLO</creatorcontrib><creatorcontrib>SIMIG GYULA DR</creatorcontrib><creatorcontrib>VERECZKEYNU DONATH GYORGYI DR</creatorcontrib><title>NOVEL PROCESS FOR THE PREPARATION OF 6-METHYL-2-(4-METHYL-PHENYL)-IMIDAZO[1,2-A]PYRIMIDYNE-3-(N,N-DIMETHYL-ACETAMIDE)</title><description>6-methyl-2-(4-methyl-phenyl)-imidazo(1,2- a)pyrimidine-3-(N,N-dimethyl-acetamide) (I) is prepared by reaction of an acetate ester (II) with dimethylamine in a polar aprotic solvent. Preparation of a compound of formula (I), or an acid addition salt of (I), comprises: (a) reaction of an ester compound of formula (II) with dimethylamine in a polar aprotic solvent; and optionally (b) converting the product (I) into an acid addition salt. R = lower alkyl or phenyl-lower alky.l Independent claims are included for: (i) esters (II), with the exception of (II; R = ethyl), and (ii) crystalline esters of formula (II).</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2011</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqFiz0LwjAYhLs4iPobzNhC36GpX2ts35JAm4Q0ClGkFImTaKH6_61QZ6e7e-5uGrylOmJJtFEZ1jUplCGW45BRM8OsUJKogmygQstdCRTC1c9rjtKVEYhK5OykzklMgV20M1_gJEIKoYwl5GI8sAwtGzqM5sHk1t57vxh1FiwLtBkH3z0b33ft1T_8q-EHSrfperdP0v-LD7q4N8k</recordid><startdate>20110428</startdate><enddate>20110428</enddate><creator>PONGO LASZLO DR</creator><creator>NAGY KALMAN DR</creator><creator>REITER JOSZEF DR</creator><creator>TOMPE PUTER DR</creator><creator>HOFFMANNU FEKETE VALURIA</creator><creator>RYVO ENDRE DR</creator><creator>KONCZ LASZLO</creator><creator>SIMIG GYULA DR</creator><creator>VERECZKEYNU DONATH GYORGYI DR</creator><scope>EVB</scope></search><sort><creationdate>20110428</creationdate><title>NOVEL PROCESS FOR THE PREPARATION OF 6-METHYL-2-(4-METHYL-PHENYL)-IMIDAZO[1,2-A]PYRIMIDYNE-3-(N,N-DIMETHYL-ACETAMIDE)</title><author>PONGO LASZLO DR ; NAGY KALMAN DR ; REITER JOSZEF DR ; TOMPE PUTER DR ; HOFFMANNU FEKETE VALURIA ; RYVO ENDRE DR ; KONCZ LASZLO ; SIMIG GYULA DR ; VERECZKEYNU DONATH GYORGYI DR</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_HU227358B13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>2011</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><toplevel>online_resources</toplevel><creatorcontrib>PONGO LASZLO DR</creatorcontrib><creatorcontrib>NAGY KALMAN DR</creatorcontrib><creatorcontrib>REITER JOSZEF DR</creatorcontrib><creatorcontrib>TOMPE PUTER DR</creatorcontrib><creatorcontrib>HOFFMANNU FEKETE VALURIA</creatorcontrib><creatorcontrib>RYVO ENDRE DR</creatorcontrib><creatorcontrib>KONCZ LASZLO</creatorcontrib><creatorcontrib>SIMIG GYULA DR</creatorcontrib><creatorcontrib>VERECZKEYNU DONATH GYORGYI DR</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>PONGO LASZLO DR</au><au>NAGY KALMAN DR</au><au>REITER JOSZEF DR</au><au>TOMPE PUTER DR</au><au>HOFFMANNU FEKETE VALURIA</au><au>RYVO ENDRE DR</au><au>KONCZ LASZLO</au><au>SIMIG GYULA DR</au><au>VERECZKEYNU DONATH GYORGYI DR</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>NOVEL PROCESS FOR THE PREPARATION OF 6-METHYL-2-(4-METHYL-PHENYL)-IMIDAZO[1,2-A]PYRIMIDYNE-3-(N,N-DIMETHYL-ACETAMIDE)</title><date>2011-04-28</date><risdate>2011</risdate><abstract>6-methyl-2-(4-methyl-phenyl)-imidazo(1,2- a)pyrimidine-3-(N,N-dimethyl-acetamide) (I) is prepared by reaction of an acetate ester (II) with dimethylamine in a polar aprotic solvent. Preparation of a compound of formula (I), or an acid addition salt of (I), comprises: (a) reaction of an ester compound of formula (II) with dimethylamine in a polar aprotic solvent; and optionally (b) converting the product (I) into an acid addition salt. R = lower alkyl or phenyl-lower alky.l Independent claims are included for: (i) esters (II), with the exception of (II; R = ethyl), and (ii) crystalline esters of formula (II).</abstract><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext_linktorsrc |
| identifier | |
| ispartof | |
| issn | |
| language | eng |
| recordid | cdi_epo_espacenet_HU227358B1 |
| source | esp@cenet |
| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS METALLURGY ORGANIC CHEMISTRY |
| title | NOVEL PROCESS FOR THE PREPARATION OF 6-METHYL-2-(4-METHYL-PHENYL)-IMIDAZO[1,2-A]PYRIMIDYNE-3-(N,N-DIMETHYL-ACETAMIDE) |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-15T17%3A51%3A12IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=PONGO%20LASZLO%20DR&rft.date=2011-04-28&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EHU227358B1%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |