AMLODIPINE BEZYLATE TABLETS HAVING EXTENDED STABILITY AND PROCESS FOR PRODUCING THE SAME

AMLODIPINE BEZYLATE TABLETS HAVING EXTENDED STABILITY AND PROCESS FOR PRODUCING THE SAME

The invention relates to amlodipine bezylate tablets with improved stability of the active ingredient and reduced in weight containing microcrystalline cellulose, a lubricant and a disintegrating agent. Said tablets comprise 4-6 % by weight of amlodipine bezylate as active ingredient together with 8...

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Bibliographische Detailangaben
Hauptverfasser: FEKETE PAL DR, LONKAINE MAGYAR OLGA, LEVENTISZNE HUSZAR MAGDOLNA, SZENTGROTI PALNE, TOEMPE PETER DR, THUROCZI PALNE, KIRALYNE IGNACZ MARIA, GORA LASZLONE
Format: Patent
Sprache:eng
Schlagworte:
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:The invention relates to amlodipine bezylate tablets with improved stability of the active ingredient and reduced in weight containing microcrystalline cellulose, a lubricant and a disintegrating agent. Said tablets comprise 4-6 % by weight of amlodipine bezylate as active ingredient together with 87 to 94 % by weight of microcrystalline cellulose, 1-5 % by weight of a disintegrating agent, 0.5 to 1.5 % by weight of a lubricant and 0.2 to 1.0 % by weight of colloidal silicon dioxide. The invention also relates to a process for the preparation of the said tablets.