PHARMACEUTICAL FORMULATION COMPRISING A 2-[[(2-PYRIDINYL)METHYL]SULFINYL] BENZIMIDAZOLE HAVING ANTI-ULCER ACTIVITY AND A PROCESS FOR THE PREPARATION OF SUCH FORMULATION

PHARMACEUTICAL FORMULATION COMPRISING A 2-[[(2-PYRIDINYL)METHYL]SULFINYL] BENZIMIDAZOLE HAVING ANTI-ULCER ACTIVITY AND A PROCESS FOR THE PREPARATION OF SUCH FORMULATION

Oral pharmaceutical formulation comprising granules having an inert core coated with a layer, comprising a 2-[[(2-pyridinyl)methyl]sulfinyl]benzimidazole having anti-ulcer activity, a disintegrant and a surfactant in a matrix of a melt coating substance essentially consisting of one or more esters o...

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Bibliographische Detailangaben
Hauptverfasser: SORENSEN, KAREN EICHSTEDT, KANN, HELLE, HENRIKSEN, KRISTIAN, PEDERSEN, SOREN BOLS
Format: Patent
Sprache:eng
Schlagworte:
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:Oral pharmaceutical formulation comprising granules having an inert core coated with a layer, comprising a 2-[[(2-pyridinyl)methyl]sulfinyl]benzimidazole having anti-ulcer activity, a disintegrant and a surfactant in a matrix of a melt coating substance essentially consisting of one or more esters of glycerol and fatty acids, a separating layer and an enteric coating layer, and a process for the preparation of such formulation using a melt coating technique for the preparation of the benzimidazole containing layer.