3,3-DIPHENYLALLYLAMINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL PREPARATIONS CONTAINING THEM

Substituted amino compounds of formula (I) and their salts are new. R1 = H, OH, O-(1-6C alkyl) or O-(3-7C cycloalkyl), provided that R1 is not H when R2 and R7 are both H or when there is an OCH3 group in the 7-position; R2 = H (if R1 is not H), OH, 1-6C alkyl, O-aryl, 2-6C alkenylene-aryl, O-(3-7C...

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Hauptverfasser:	FRIDERICHS, ELMAR JOSEF DR, BUSCHMANN, HELMUT HEINRICH DR, STRASSBURGER, WOLFGANG WERNER ALFRED DR, ZIMMER, OSWALD DR, ENGLBERGER, WERNER DR
Format:	Patent
Sprache:	eng
Schlagworte:	ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	Substituted amino compounds of formula (I) and their salts are new. R1 = H, OH, O-(1-6C alkyl) or O-(3-7C cycloalkyl), provided that R1 is not H when R2 and R7 are both H or when there is an OCH3 group in the 7-position; R2 = H (if R1 is not H), OH, 1-6C alkyl, O-aryl, 2-6C alkenylene-aryl, O-(3-7C cycloalkyl), Cl, F, 1-6C alkoxy, aryl, heterocyclyl, 1-6C alkyl-heterocyclyl, 1-6C alkyl-aryl, 5,6- or 6,7-benzo (which is optionally substituted by 1 or 2 Cl, F, CF3, 1-6C alkyl, 1-6C alkoxy or OH groups); or R2+R7 = O-(CH2)-O or O-(CH2)2-O in the 5,6- or 6,7- position; provided that when R1 and R2 or R7 are H, R2 or R7 are not CF3 and R2 or R7 cannot be a 7-OCH3 group; R3 = H; R4 = 1-6C alkyl; or R3+R4 = (CH2)1-4; R5 = 1-6C alkyl or 3-7C cycloalkyl; R6 = 1-6C alkyl, 1-6C alkyl-aryl, 1-6C alkyl-heterocyclyl, -CH2-CH=C(R8)2, -CH2-(3-7C cycloalkyl) or 3-7C cycloalkyl; R7 = H (if R1 is not H), OH, 1-6C alkyl, O-aryl, 2-6C alkenylene-aryl, O-(3-7C cycloalkyl), Cl, F, 1-6C alkoxy, aryl, heterocyclyl, 1-6C alkyl-heterocyclyl, 1-6C alkyl-aryl, 5,6- or 6,7-benzo (which is optionally substituted by 1 or 2 Cl, F, CF3, 1-6C alkyl, 1-6C alkoxy or OH groups; R8 = H or CH3.