VISUALLY-READABLE REAGENT TEST STRIP

A multilayer reagent test strip measures the concentration of analyte in a liquid sample that is applied to it. The sample is guided to a number of assay areas arrayed along the strip, where the analyte can react with a reagent to cause a color change. Each assay area also includes an inhibitor for...

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Bibliographische Detailangaben
Hauptverfasser: WITKO, ZBIGNIEW, TUOHY, DEBORAH P, SEGELKE, SCOTT, DOUGLAS, JOEL, KISER, ERNEST, MAXSON, MARK, TOMASCO, MICHAEL F, DATO, REMEDIOS, RICE, EDWARD G
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:A multilayer reagent test strip measures the concentration of analyte in a liquid sample that is applied to it. The sample is guided to a number of assay areas arrayed along the strip, where the analyte can react with a reagent to cause a color change. Each assay area also includes an inhibitor for the color-change reaction. The inhibitor concentration increases in successive assay areas; thus, the number of areas that change color is a measure of the analyte concentration. The test strip is particularly adapted for measuring glucose in a whole blood sample. In a preferred embodiment, the sample is guided to the assay areas along a path formed by crushing selected areas of a membrane, and the assay areas are uncrushed areas of the membrane.