PROCESS TO PREPARARE PHARMACEUTICAL COMPNS. WITH GASTROPROTECTIVE AND ANTI HELICOBACTER PYLORI ACTIVITY

The subject-matter of the invention is the use of 2-[phenylmethylene]-1-[3'-(amino)-2'-(hydroxy)-propoxy-imino]-cyclohexane derviates of formula wherein R and R1 independently mean hydrogen or halogen atom(s), Ro stands for hydrogen or a C1-4 alkoxy group, R2 and R3 independently represent hydrogen atom(s), straight and/or branched chain C1-8 alkyl group(s), optionally substituted by a dimethylamino group, or C2-6 alkenyl or C3-7 cycloalkyl group(s) or R2 and R3 together with the nitrogen atom to which they are attached form a 6-membered heterocyclic group containing an additional nitrogen atom, which latter optionally may bear a phenyl group, optionally substituted by a C1-4 alkoxy group, and their stereoisomers and optical isomers and mixtures thereof as well as pharmaceutically acceptable acid addition salts and quaternary ammonium derivatives thereof, optionally in admixture with 1 or more carrier(s) commonly used in pharmaceutical compositions, for preparing medicaments having gastroprotective and antimicrobial including antiulcer activity.