PHARMACEUTICAL COMPOSITION AND PROCESS FOR THE PREPARATION THEREOF

PHARMACEUTICAL COMPOSITION AND PROCESS FOR THE PREPARATION THEREOF

PCT No. PCT/HU92/00060 Sec. 371 Date Jun. 17, 1994 Sec. 102(e) Date Jun. 17, 1994 PCT Filed Dec. 18, 1992 PCT Pub. No. WO93/12775 PCT Pub. Date Jul. 8, 1993The invention relates to two phase pharmaceutical compositions comprising as active ingredient a MAO inhibitor and an uptake inhibitor together...

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Bibliographische Detailangaben
Hauptverfasser: LENGYEL JOZSEF, MAGYAR KALMAN, GAAL JOZSEF, MARMAROSI TAMASNE, HERMECZ ISTVAN, SZIRAKI ISTVAN, KOERMOECZY PETER, TOEROEK ZOLTAN, Z. SZABO ANNA, SZATMARI ISTVAN
Format: Patent
Sprache:eng
Schlagworte:
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:PCT No. PCT/HU92/00060 Sec. 371 Date Jun. 17, 1994 Sec. 102(e) Date Jun. 17, 1994 PCT Filed Dec. 18, 1992 PCT Pub. No. WO93/12775 PCT Pub. Date Jul. 8, 1993The invention relates to two phase pharmaceutical compositions comprising as active ingredient a MAO inhibitor and an uptake inhibitor together with usual pharmaceutical auxiliaries. The compositions can be used for the treatment of neurodegenerative diseases. As active ingredient optionally N-(1-phenyl-isopropyl)-N-methyl-propinylamine or N-(4-fluoro-phenyl)-isoprop-1-yl-N-methyl-propinylamine or their salts, optically active isomers or metabolites are used both as MAO inhibitor and as uptake inhibitor.