PROCESS FOR THE PREPARATION OF ACETIC ACID-(TRIFLUOROMETHANESULFONIC ACID) MIXED ANHYDRIDE DERIVATIVES

A process is disclosed for the preparation of a compound of the Formula (VI) (VI) wherein X is a hydrogen atom, or OH, Y is a hydrogen atom, OH or a methyl group, R2 is a CH-COOR group, or a group of the formula (XI) (XI) and R is a C1 to C2 alkyl group, which comprises the step of: reacting a conde...

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Hauptverfasser: KRUPPA,MARTA, BAN,KAROLY, BAN,ANNAMARIA, SOMFAI,EVA, HUSZAR,CSABA, PALI,LAJOSNE
Format: Patent
Sprache:eng
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Zusammenfassung:A process is disclosed for the preparation of a compound of the Formula (VI) (VI) wherein X is a hydrogen atom, or OH, Y is a hydrogen atom, OH or a methyl group, R2 is a CH-COOR group, or a group of the formula (XI) (XI) and R is a C1 to C2 alkyl group, which comprises the step of: reacting a condensed salt of the Formula (IV) (IV) wherein Me is Na+ or K+, with a reactive derivative of trifluoromethane-sulfonic acid of the Formula (V) F3C-SO2OH. The compounds of the Formula (VI) are intermediates in the preparation of penicillins and cephalosporins with antibiotic activity.