PROCESS FOR PRODUCING NEW OLIGOPEPTIDES WHICH SELECTIVELY INHIBIT PROLIFERATION OF HAEMOPOIETIC CELLS AND PHARMACEUTICAL COMPOSITIONS COMPRISING SAME

PROCESS FOR PRODUCING NEW OLIGOPEPTIDES WHICH SELECTIVELY INHIBIT PROLIFERATION OF HAEMOPOIETIC CELLS AND PHARMACEUTICAL COMPOSITIONS COMPRISING SAME

The present invention relates to peptides of formulae (1) Glp-Glu-Asp-Cys(Acm)-Lys-OH and (2) H-Glu-Asp-Cys(Acm)-Lys-OH wherein Acm represents an acetamidomethyl group, the acid addition salts thereof, pharmaceutical compositions comprising the same and processes for their preparation. The peptides...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: BALAZS,ANDRAS,HU, SCHOEN,ISTVAN,HU, KISFALUDY,LAJOS,HU, SZIRTES,TAMAS,HU
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:The present invention relates to peptides of formulae (1) Glp-Glu-Asp-Cys(Acm)-Lys-OH and (2) H-Glu-Asp-Cys(Acm)-Lys-OH wherein Acm represents an acetamidomethyl group, the acid addition salts thereof, pharmaceutical compositions comprising the same and processes for their preparation. The peptides selectively inhibit the proliferation of hemopoietic cells.