PROCESS FOR PRODUCING AND USING NEW GENE MARKED BY T1RB, ENSURING TYLOSIN RESISTANCE AND APPLICABLE WITHIN THE DOMAIN OF STREPTOMYCES AND OTHER MICROORGANISMS

The tirB gene is a novel tylosin resistance-conferring gene isolated from Streptomyces fradiae and used to construct a number of cloning vectors for use in Streptomyces and related organisms. One such cloning vector, plasmid pSVB9, can be obtained in S. lividans under the accession number NRRL 18037...

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Bibliographische Detailangaben
Hauptverfasser: SENO,EUGENE THOMAS,US, BIRMINGHAM,VIRGINIA ANN,US
Format: Patent
Sprache:eng
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Zusammenfassung:The tirB gene is a novel tylosin resistance-conferring gene isolated from Streptomyces fradiae and used to construct a number of cloning vectors for use in Streptomyces and related organisms. One such cloning vector, plasmid pSVB9, can be obtained in S. lividans under the accession number NRRL 18037. S. lividans is the preferred host when the tlrB gene is used to select tylosin-resistant Streptomyces transformants.