PROCESS FOR PRODUCING CRYSTALLINE CEFALOSPORINHYDRATE AND CAPSULES COMPRISING SAME

An antibacterial, 7 beta -[(Z)-2-(2-aminothiazol-4-yl)-4-carboxybut-2-enoylamino]-3-cephem-4-ca rboxylic acid is stable in a (di or tri)-hydrate crystal form. A pharmacologically effective amount of this hydrate is filled in a gelatin hard capsule sealed by a band of gelatin to make a stable composi...

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Hauptverfasser: SUZUKI,YUSUKE,JP, MINAMI,KYOJI,JP, TAKEDA,TOYOHIKO,JP, HAMASHIMA,YOSHIO,JP, SAKAMOTO,TERUO,JP, KAWATA,KYOZO,JP, TUJIKAWA,MASANORI,JP
Format: Patent
Sprache:eng
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Zusammenfassung:An antibacterial, 7 beta -[(Z)-2-(2-aminothiazol-4-yl)-4-carboxybut-2-enoylamino]-3-cephem-4-ca rboxylic acid is stable in a (di or tri)-hydrate crystal form. A pharmacologically effective amount of this hydrate is filled in a gelatin hard capsule sealed by a band of gelatin to make a stable composition for clinical use after storage for a long time.