PROCESS FOR PRODUCING ANTITUMOUR PLATINUM COMPLEXES AND PHARMACEUTICAL COMPOSITIONS COMPRISING SAME

PROCESS FOR PRODUCING ANTITUMOUR PLATINUM COMPLEXES AND PHARMACEUTICAL COMPOSITIONS COMPRISING SAME

Compounds of formula (I): in which: A and B are separately monoamines or together diamines; and Z is a group of formula (II) or (III): (in which R , R and R are various organic groups, n is 0, 1 or 2 and X is a direct carbon-carbon bond or lower alkylene) show valuable anti-tumour activity and may b...

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Bibliographische Detailangaben
Hauptverfasser: SHIBATA,TOMOYUKI,JP, HASHIMOTO,TOSHIHIKO,JP, KAMEYAMA,YUKIHO,JP, KOBAYASHI,TOMOWO,JP, IINO,KIMIO,JP, SUGIMURA,YUKIO,JP, MURAMATSU,SHIGEKI,JP
Format: Patent
Sprache:eng
Schlagworte:
ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
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Zusammenfassung:Compounds of formula (I): in which: A and B are separately monoamines or together diamines; and Z is a group of formula (II) or (III): (in which R , R and R are various organic groups, n is 0, 1 or 2 and X is a direct carbon-carbon bond or lower alkylene) show valuable anti-tumour activity and may be prepared by reacting an amine-platinum complex with a compound providing the group represented by Z.