PROCESS FOR PRODUCTION OF DERIVATIVES OF BENZOL-SULFHONAMID AND MEDICAL COMPOSITIONS CONTAINING THEM AS ACTIVE SUBSTANCE

PROCESS FOR PRODUCTION OF DERIVATIVES OF BENZOL-SULFHONAMID AND MEDICAL COMPOSITIONS CONTAINING THEM AS ACTIVE SUBSTANCE

This invention provides the use of certain benzenesulfonamide derivatives of the formula (I) wherein: R1 and R3 are independently hydrogen, C1-C3 alkyl, halo, trifluoromethyl, or C1-C3 alkoxy; R2 is halo, methyl, or trifluoromethyl; and R4 is hydrogen, halo, methyl, or trifluoromethyl, in the treatm...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: RIEDER,BRENT J.,US, HARPER,RICHARD W.,US, POORE,GERALD A.,US
Format: Patent
Sprache:eng
Schlagworte:
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:This invention provides the use of certain benzenesulfonamide derivatives of the formula (I) wherein: R1 and R3 are independently hydrogen, C1-C3 alkyl, halo, trifluoromethyl, or C1-C3 alkoxy; R2 is halo, methyl, or trifluoromethyl; and R4 is hydrogen, halo, methyl, or trifluoromethyl, in the treatment of susceptible neoplasms in mammals. Also provided are certain novel benzenesulfonamide derivatives and their pharmaceutical formulations.