PROCESS FOR PRODUCTION OF NEW /3.2.0/-BICYCLOHEPTHANONOXIM ETHERS AND MEDICAL COMPOSITIONS CONTAINING THESE ACTIVE SUBSTANCES

Compounds useful in treating cardiovascular disorders are the carboxylic acids depicted in formulas (1) and (2)as well as their pharmaceutically acceptable, non-toxic salts and esters, wherein:n is an integer from one to four;R1 is hydroxy;R2 is hydrogen; orR1 and Rz together are an oxo group;R3 isw...

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Bibliographische Detailangaben
Hauptverfasser:	MARX,MICHAEL,US, LI,TSUNG-TEE,US
Format:	Patent
Sprache:	eng
Schlagworte:	ACYCLIC OR CARBOCYCLIC COMPOUNDS ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	Compounds useful in treating cardiovascular disorders are the carboxylic acids depicted in formulas (1) and (2)as well as their pharmaceutically acceptable, non-toxic salts and esters, wherein:n is an integer from one to four;R1 is hydroxy;R2 is hydrogen; orR1 and Rz together are an oxo group;R3 iswhereinA is -CH2-CH2-; trans-CH=CH-; -C≡C-; andR4 is linear or branched alkyl of one to twelve carbons, cycloalkyl of three to eight carbons; phenyl optionally substituted with one or two identical substituents selected from the group consisting of lower alkyl, lower alkoxy, hydroxy, trifluoromethyl, and halo; or optionally substituted phenylalkyl.