PROCESS FOR PREPARING 1,4-DIHYDRO-PYRIDINA DERIVATIVES

Compounds of the formula:where R is an optionally substituted aryl or heteroaryl group;R1 and R are each independently C1-C4 alkyl or 2-methoxyethyl; and Y is -(CH2)n- where n is 2, 3 or 4, -CH2CH(CH3)-or -CH2C(CH3)2-; and their pharmaceutically acceptable salts.The compounds have utility as anti-is...

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Hauptverfasser:	CROSS,PETER E.,GB, ALKER,DAVID,GB, CAMPBELL,SIMON F.,GB
Format:	Patent
Sprache:	eng
Schlagworte:	ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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creator	CROSS,PETER E.,GB ALKER,DAVID,GB CAMPBELL,SIMON F.,GB
description	Compounds of the formula:where R is an optionally substituted aryl or heteroaryl group;R1 and R are each independently C1-C4 alkyl or 2-methoxyethyl; and Y is -(CH2)n- where n is 2, 3 or 4, -CH2CH(CH3)-or -CH2C(CH3)2-; and their pharmaceutically acceptable salts.The compounds have utility as anti-ischaemic and antihypertensive agents and as synthetic intermediates to other dihydropyridine calcium antagonists.
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subjects	ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title	PROCESS FOR PREPARING 1,4-DIHYDRO-PYRIDINA DERIVATIVES
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