PROCESS FOR PREPARING 1,4-DIHYDRO-PYRIDINA DERIVATIVES

Compounds of the formula:where R is an optionally substituted aryl or heteroaryl group;R1 and R are each independently C1-C4 alkyl or 2-methoxyethyl; and Y is -(CH2)n- where n is 2, 3 or 4, -CH2CH(CH3)-or -CH2C(CH3)2-; and their pharmaceutically acceptable salts.The compounds have utility as anti-is...

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Bibliographische Detailangaben
Hauptverfasser:	CROSS,PETER E.,GB, ALKER,DAVID,GB, CAMPBELL,SIMON F.,GB
Format:	Patent
Sprache:	eng
Schlagworte:	ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	Compounds of the formula:where R is an optionally substituted aryl or heteroaryl group;R1 and R are each independently C1-C4 alkyl or 2-methoxyethyl; and Y is -(CH2)n- where n is 2, 3 or 4, -CH2CH(CH3)-or -CH2C(CH3)2-; and their pharmaceutically acceptable salts.The compounds have utility as anti-ischaemic and antihypertensive agents and as synthetic intermediates to other dihydropyridine calcium antagonists.