PROCESS FOR PRODUCING SPIRO/2H-1,4-BENZODIOXEPINE-3/5H/, 4-COMMA ABOVE-PIPERIDINE/ COMPOUNDS

PROCESS FOR PRODUCING SPIRO/2H-1,4-BENZODIOXEPINE-3/5H/, 4-COMMA ABOVE-PIPERIDINE/ COMPOUNDS

Spiro[2H-1,4-benzodioxepin-3(5H)4'-piperidine and -3-pyrrolidine] compounds of the formulawhere the substituents are as defined herein, are useful in the treatment of hypertension and alleviation of pain in mammals. Such compounds, their use as antihypertensive and analgesic agents, pharmaceuti...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: CHERILL,J.,ROBERT,US, KOSLEY,W.,RAYMOND,US
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:Spiro[2H-1,4-benzodioxepin-3(5H)4'-piperidine and -3-pyrrolidine] compounds of the formulawhere the substituents are as defined herein, are useful in the treatment of hypertension and alleviation of pain in mammals. Such compounds, their use as antihypertensive and analgesic agents, pharmaceutical compositions containing the compounds, intermediates and processes for prepar- ing the compounds are provided.