PROCESS FOR PREPARING 3-AMINO-THIOPHENE-4-CARBOXYLIC ACID DERIVATIVES

PROCESS FOR PREPARING 3-AMINO-THIOPHENE-4-CARBOXYLIC ACID DERIVATIVES

Hypolipaemic 3-aminothiophenes of the formula in which R1 is lower alkyl, aryl or aralkyl and R2 is lower alkoxy, and salts thereof are prepared starting from the corresponding 3-ketotetrahydrothiophene oximes. The resulting compounds of the formula I can be converted into the corresponding carboxyl...

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Bibliographische Detailangaben
Hauptverfasser: USKOVIC,MILAN,R.,US, PIZZOLOTO,GIACOMO,US, ROUGE,MARIANNE,CH, CONFALONE,PASQUALE,N.,US
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:Hypolipaemic 3-aminothiophenes of the formula in which R1 is lower alkyl, aryl or aralkyl and R2 is lower alkoxy, and salts thereof are prepared starting from the corresponding 3-ketotetrahydrothiophene oximes. The resulting compounds of the formula I can be converted into the corresponding carboxylic acids or N-alkylated or N-aralkylated.