CRYSTALLINE FORMS OF ENDO-2,3-DIHYDRO-N-(8-METHYL-8-AZABICYCLO (3.2.1)OCT-3-YL)-2-OXO-1H-BENZIMIDAZOLE-1-CARBOXAMIDE HYDROCHLORIDE MONOHYDRATE AND OF ENDO-3-ETHYL-2,3-DIHYDRO-N-(8-METHYL-8-AZABICYCLO (3.2.1)OCT-3-YL)-2-OXO-1H-BENZIMIDAZOLE-1-CARBOXAMIDE HYDROCHLORIDE MONOHYDRATE

CRYSTALLINE FORMS OF ENDO-2,3-DIHYDRO-N-(8-METHYL-8-AZABICYCLO (3.2.1)OCT-3-YL)-2-OXO-1H-BENZIMIDAZOLE-1-CARBOXAMIDE HYDROCHLORIDE MONOHYDRATE AND OF ENDO-3-ETHYL-2,3-DIHYDRO-N-(8-METHYL-8-AZABICYCLO (3.2.1)OCT-3-YL)-2-OXO-1H-BENZIMIDAZOLE-1-CARBOXAMIDE HYDROCHLORIDE MONOHYDRATE

Crystalline monohydrates of endo-2,3-dihydro-N-(8-methyl-8-azabicyclo[3.2.1]oct-3-yl)-2-oxo-1H-ben zimidazole-1-carboxamide hydrochloride and of endo-3-ethyl-2,3-dihydro-N-(8-methyl-8-azabicyclo[3.2.1]oct-3-yl)-2-ox o-1H-benzimidazole-1-carboxamide hydrochloride of formula (Compound 2a: R = H> (C...

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Bibliographische Detailangaben
1. Verfasser: MARCO TURCONI
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:Crystalline monohydrates of endo-2,3-dihydro-N-(8-methyl-8-azabicyclo[3.2.1]oct-3-yl)-2-oxo-1H-ben zimidazole-1-carboxamide hydrochloride and of endo-3-ethyl-2,3-dihydro-N-(8-methyl-8-azabicyclo[3.2.1]oct-3-yl)-2-ox o-1H-benzimidazole-1-carboxamide hydrochloride of formula (Compound 2a: R = H> (Compound 2b: R = C2H5> the processes for their preparation and pharmaceutical compositions containing them.