CRF2 RECEPTOR AGONISTS AND THEIR USE IN THERAPY
The present disclosure provides compounds which are peptides comprising the amino acid sequence of the formula (I) disclosed herein or pharmaceutically acceptable salts thereof. The compounds act as agonists of the corticotropin-releasing factor receptor 2 (CRF2) and are useful in therapy, especiall...
Gespeichert in:
| Hauptverfasser: | , , , , , , , , , , , , , |
|---|---|
| Format: | Patent |
| Sprache: | hrv ; eng |
| Schlagworte: | |
| Online-Zugang: | Volltext bestellen |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | |
| container_start_page | |
| container_title | |
| container_volume | |
| creator | Li, Ziyu Elvert, Ralf Illiano, Stephane Tripepi, Martina Roversi, Daniela Evers, Andreas Santoprete, Alessia Lucats, Laurence Ledein, Laetitia Ozoux, Marie-Laure Bianchi, Elisabetta Halland, Nis Beauverger, Philippe Janiak, Philip |
| description | The present disclosure provides compounds which are peptides comprising the amino acid sequence of the formula (I) disclosed herein or pharmaceutically acceptable salts thereof. The compounds act as agonists of the corticotropin-releasing factor receptor 2 (CRF2) and are useful in therapy, especially in the treatment or prevention of cardiovascular diseases, obesity and diabetes. |
| format | Patent |
| fullrecord | <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_HRP20240906TT1</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>HRP20240906TT1</sourcerecordid><originalsourceid>FETCH-epo_espacenet_HRP20240906TT13</originalsourceid><addsrcrecordid>eNrjZNB3DnIzUghydXYNCPEPUnB09_fzDA4JVnD0c1EI8XD1DFIIDXZV8PQDcYIcAyJ5GFjTEnOKU3mhNDeDsptriLOHbmpBfnxqcUFicmpeakm8R1CAkYGRiYGlgVlIiKExcaoAjh0nMw</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>CRF2 RECEPTOR AGONISTS AND THEIR USE IN THERAPY</title><source>esp@cenet</source><creator>Li, Ziyu ; Elvert, Ralf ; Illiano, Stephane ; Tripepi, Martina ; Roversi, Daniela ; Evers, Andreas ; Santoprete, Alessia ; Lucats, Laurence ; Ledein, Laetitia ; Ozoux, Marie-Laure ; Bianchi, Elisabetta ; Halland, Nis ; Beauverger, Philippe ; Janiak, Philip</creator><creatorcontrib>Li, Ziyu ; Elvert, Ralf ; Illiano, Stephane ; Tripepi, Martina ; Roversi, Daniela ; Evers, Andreas ; Santoprete, Alessia ; Lucats, Laurence ; Ledein, Laetitia ; Ozoux, Marie-Laure ; Bianchi, Elisabetta ; Halland, Nis ; Beauverger, Philippe ; Janiak, Philip</creatorcontrib><description>The present disclosure provides compounds which are peptides comprising the amino acid sequence of the formula (I) disclosed herein or pharmaceutically acceptable salts thereof. The compounds act as agonists of the corticotropin-releasing factor receptor 2 (CRF2) and are useful in therapy, especially in the treatment or prevention of cardiovascular diseases, obesity and diabetes.</description><language>hrv ; eng</language><subject>CHEMISTRY ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PEPTIDES ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2024</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20241011&DB=EPODOC&CC=HR&NR=P20240906T1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,309,781,886,25569,76552</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20241011&DB=EPODOC&CC=HR&NR=P20240906T1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>Li, Ziyu</creatorcontrib><creatorcontrib>Elvert, Ralf</creatorcontrib><creatorcontrib>Illiano, Stephane</creatorcontrib><creatorcontrib>Tripepi, Martina</creatorcontrib><creatorcontrib>Roversi, Daniela</creatorcontrib><creatorcontrib>Evers, Andreas</creatorcontrib><creatorcontrib>Santoprete, Alessia</creatorcontrib><creatorcontrib>Lucats, Laurence</creatorcontrib><creatorcontrib>Ledein, Laetitia</creatorcontrib><creatorcontrib>Ozoux, Marie-Laure</creatorcontrib><creatorcontrib>Bianchi, Elisabetta</creatorcontrib><creatorcontrib>Halland, Nis</creatorcontrib><creatorcontrib>Beauverger, Philippe</creatorcontrib><creatorcontrib>Janiak, Philip</creatorcontrib><title>CRF2 RECEPTOR AGONISTS AND THEIR USE IN THERAPY</title><description>The present disclosure provides compounds which are peptides comprising the amino acid sequence of the formula (I) disclosed herein or pharmaceutically acceptable salts thereof. The compounds act as agonists of the corticotropin-releasing factor receptor 2 (CRF2) and are useful in therapy, especially in the treatment or prevention of cardiovascular diseases, obesity and diabetes.</description><subject>CHEMISTRY</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PEPTIDES</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2024</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZNB3DnIzUghydXYNCPEPUnB09_fzDA4JVnD0c1EI8XD1DFIIDXZV8PQDcYIcAyJ5GFjTEnOKU3mhNDeDsptriLOHbmpBfnxqcUFicmpeakm8R1CAkYGRiYGlgVlIiKExcaoAjh0nMw</recordid><startdate>20241011</startdate><enddate>20241011</enddate><creator>Li, Ziyu</creator><creator>Elvert, Ralf</creator><creator>Illiano, Stephane</creator><creator>Tripepi, Martina</creator><creator>Roversi, Daniela</creator><creator>Evers, Andreas</creator><creator>Santoprete, Alessia</creator><creator>Lucats, Laurence</creator><creator>Ledein, Laetitia</creator><creator>Ozoux, Marie-Laure</creator><creator>Bianchi, Elisabetta</creator><creator>Halland, Nis</creator><creator>Beauverger, Philippe</creator><creator>Janiak, Philip</creator><scope>EVB</scope></search><sort><creationdate>20241011</creationdate><title>CRF2 RECEPTOR AGONISTS AND THEIR USE IN THERAPY</title><author>Li, Ziyu ; Elvert, Ralf ; Illiano, Stephane ; Tripepi, Martina ; Roversi, Daniela ; Evers, Andreas ; Santoprete, Alessia ; Lucats, Laurence ; Ledein, Laetitia ; Ozoux, Marie-Laure ; Bianchi, Elisabetta ; Halland, Nis ; Beauverger, Philippe ; Janiak, Philip</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_HRP20240906TT13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>hrv ; eng</language><creationdate>2024</creationdate><topic>CHEMISTRY</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PEPTIDES</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>Li, Ziyu</creatorcontrib><creatorcontrib>Elvert, Ralf</creatorcontrib><creatorcontrib>Illiano, Stephane</creatorcontrib><creatorcontrib>Tripepi, Martina</creatorcontrib><creatorcontrib>Roversi, Daniela</creatorcontrib><creatorcontrib>Evers, Andreas</creatorcontrib><creatorcontrib>Santoprete, Alessia</creatorcontrib><creatorcontrib>Lucats, Laurence</creatorcontrib><creatorcontrib>Ledein, Laetitia</creatorcontrib><creatorcontrib>Ozoux, Marie-Laure</creatorcontrib><creatorcontrib>Bianchi, Elisabetta</creatorcontrib><creatorcontrib>Halland, Nis</creatorcontrib><creatorcontrib>Beauverger, Philippe</creatorcontrib><creatorcontrib>Janiak, Philip</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>Li, Ziyu</au><au>Elvert, Ralf</au><au>Illiano, Stephane</au><au>Tripepi, Martina</au><au>Roversi, Daniela</au><au>Evers, Andreas</au><au>Santoprete, Alessia</au><au>Lucats, Laurence</au><au>Ledein, Laetitia</au><au>Ozoux, Marie-Laure</au><au>Bianchi, Elisabetta</au><au>Halland, Nis</au><au>Beauverger, Philippe</au><au>Janiak, Philip</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>CRF2 RECEPTOR AGONISTS AND THEIR USE IN THERAPY</title><date>2024-10-11</date><risdate>2024</risdate><abstract>The present disclosure provides compounds which are peptides comprising the amino acid sequence of the formula (I) disclosed herein or pharmaceutically acceptable salts thereof. The compounds act as agonists of the corticotropin-releasing factor receptor 2 (CRF2) and are useful in therapy, especially in the treatment or prevention of cardiovascular diseases, obesity and diabetes.</abstract><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext_linktorsrc |
| identifier | |
| ispartof | |
| issn | |
| language | hrv ; eng |
| recordid | cdi_epo_espacenet_HRP20240906TT1 |
| source | esp@cenet |
| subjects | CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | CRF2 RECEPTOR AGONISTS AND THEIR USE IN THERAPY |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-12T03%3A30%3A09IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=Li,%20Ziyu&rft.date=2024-10-11&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EHRP20240906TT1%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |