CRF2 RECEPTOR AGONISTS AND THEIR USE IN THERAPY

CRF2 RECEPTOR AGONISTS AND THEIR USE IN THERAPY

The present disclosure provides compounds which are peptides comprising the amino acid sequence of the formula (I) disclosed herein or pharmaceutically acceptable salts thereof. The compounds act as agonists of the corticotropin-releasing factor receptor 2 (CRF2) and are useful in therapy, especiall...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Li, Ziyu, Elvert, Ralf, Illiano, Stephane, Tripepi, Martina, Roversi, Daniela, Evers, Andreas, Santoprete, Alessia, Lucats, Laurence, Ledein, Laetitia, Ozoux, Marie-Laure, Bianchi, Elisabetta, Halland, Nis, Beauverger, Philippe, Janiak, Philip
Format: Patent
Sprache:hrv ; eng
Schlagworte:
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:The present disclosure provides compounds which are peptides comprising the amino acid sequence of the formula (I) disclosed herein or pharmaceutically acceptable salts thereof. The compounds act as agonists of the corticotropin-releasing factor receptor 2 (CRF2) and are useful in therapy, especially in the treatment or prevention of cardiovascular diseases, obesity and diabetes.