BISPECIFIC T CELL ACTIVATING ANTIGEN BINDING MOLECULES

The present invention generally relates to novel bispecific antigen binding molecules for T cell activation and re-direction to specific target cells. In addition, the present invention relates to polynucleotides encoding such bispecific antigen binding molecules, and vectors and host cells comprisi...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Neumann (formally Jaeger), Christiane, Klostermann, Stefan, Regula, Joerg Thomas, Molhoj, Michael, Ast, Oliver, Imhof-Jung, Sabine, Klein, Christian, Umaña, Pablo, Bacac, Marina, Schaefer, Wolfgang
Format: Patent
Sprache:hrv ; eng
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Beschreibung
Zusammenfassung:The present invention generally relates to novel bispecific antigen binding molecules for T cell activation and re-direction to specific target cells. In addition, the present invention relates to polynucleotides encoding such bispecific antigen binding molecules, and vectors and host cells comprising such polynucleotides. The invention further relates to methods for producing the bispecific antigen binding molecules of the invention, and to methods of using these bispecific antigen binding molecules in the treatment of disease.