HIGHLY CONCENTRATED PHARMACEUTICAL FORMULATIONS

The present invention claims high dose CD20 antibody subcutaneous formulations together with hyaluronidase. Preferred antibodies are MabThera, Ocrelizumab and GA101, preferably in a dose of 120 mg/ml. The preferred hyaluronidase is Halozyme.

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Bibliographische Detailangaben
Hauptverfasser:	Adler, Michael, Mahler, Hanns-Christian, Stauch, Oliver Boris
Format:	Patent
Sprache:	hrv ; eng
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention claims high dose CD20 antibody subcutaneous formulations together with hyaluronidase. Preferred antibodies are MabThera, Ocrelizumab and GA101, preferably in a dose of 120 mg/ml. The preferred hyaluronidase is Halozyme.