SUBSTITUTED BICYCLIC HETEROCYCLIC COMPOUNDS AS PRMT5 INHIBITORS

The invention relates to substituted bicyclic heterocyclic compounds of formula (I), pharmaceutically acceptable salts thereof and pharmaceutical compositions for treating diseases, disorders or conditions associated with the overexpression of PRMT5 enzyme. The invention also relates to methods of t...

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Hauptverfasser: Hajare, Anil Kashiram, Palle, Venkata P, Gore, Balasaheb Arjun, Sindkhedkar, Milind Dattatraya, Nair, Prathap Sreedharan, Sethi, Sachin, Kamboj, Rajender Kumar, Lagad, Dipak Raychand, Gudade, Ganesh Bhausaheb, Kulkarni, Chaitanya Prabhakar, Pawar, Chetan Sanjay, Tryambake, Mahadeo Bhaskar, Kulkarni, Sanjeev Anant
Format: Patent
Sprache:hrv ; eng
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Zusammenfassung:The invention relates to substituted bicyclic heterocyclic compounds of formula (I), pharmaceutically acceptable salts thereof and pharmaceutical compositions for treating diseases, disorders or conditions associated with the overexpression of PRMT5 enzyme. The invention also relates to methods of treating diseases, disorders or conditions associated with the overexpression of PRMT5 enzyme.