METHOD AND COMPOSITION FOR TREATING OCULAR HYPERTENSION AND GLAUCOMA

The present invention relates to a method for increasing aqueous solubility and improving stability of tafluprost in an aqueous ophthalmic solution, comprising the steps of preparing an aqueous ophthalmic solution containing 0.0010-0.0025% tafluprost, 0.075% polysorbate 80, 0.005-0.2% stabilizing ag...

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Bibliographische Detailangaben
Hauptverfasser: Pellinen, Pertti, Oksala, Olli, Reunamaki, Timo, Lehmussaari, Kari
Format: Patent
Sprache:hrv ; eng
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Zusammenfassung:The present invention relates to a method for increasing aqueous solubility and improving stability of tafluprost in an aqueous ophthalmic solution, comprising the steps of preparing an aqueous ophthalmic solution containing 0.0010-0.0025% tafluprost, 0.075% polysorbate 80, 0.005-0.2% stabilizing agent and substantially no preservatives, and packaging the preservative-free ophthalmic solution in a container consisting essentially of polyethylene.