1H-INDAZOLE-3-CARBOXAMIDE DERIVATIVES AND RELATED COMPOUNDS AS FACTOR D INHIBITORS FOR TREATING DISEASES CHARACTERIZED BY ABERRANT COMPLEMENT SYSTEM ACTIVITY, SUCH AS E.G. IMMUNOLOGICAL DISORDERS

Disclosed are compounds of formula I, and pharmaceutically acceptable salts thereof.The compounds are inhibitors of the complement system, and more specifically of the factor D.Also provided are pharmaceutical compositions comprising a compound of formula I, and the compounds of formula I for use in...

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Bibliographische Detailangaben
Hauptverfasser:	Kotian, Pravin L, Chintareddy, Venkat R, Vogeti, Lakshminarayana, Raman, Krishnan, Babu, Yarlagadda S, Zhang, Weihe, Wu, Minwan
Format:	Patent
Sprache:	hrv ; eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	Disclosed are compounds of formula I, and pharmaceutically acceptable salts thereof.The compounds are inhibitors of the complement system, and more specifically of the factor D.Also provided are pharmaceutical compositions comprising a compound of formula I, and the compounds of formula I for use in methods for the treatment and prevention of diseases and conditions characterized by aberrant complement system activity, such as e.g. immunological disorders.